USE OF UMIROLIMUS AND ITS DERIVATIVES FOR TREATING CANCER

摘要

Novel encapsulated umirolimus and umirolimus polymer conjugate formulations having enhanced permeability and retention at tumor sites. Also provided are methods for treating cancer by administering the umirolimus formulations.

主权项

1. A pharmaceutical formulation comprising umirolimus encapsulated in a liposome or a polymer micelle, and a pharmaceutically acceptable excipient, carrier, or diluent, wherein the liposome or the polymer micelle has a particle size of 10-200 nm.