摘要 |
The present invention relates to pharmaceutical compositions comprising a prostacyclin, a cationic compound, and a surfactant. Particulate compositions, including liposomal, solid nanoparticulate prostacyclin compositions, including treprostinil formulations comprising cationic compound and the surfactant are also described. The present invention also relates to a system comprising the pharmaceutical composition and an inhalation device. Methods for treating pulmonary hypertension and portopulmonary hypertension with the compositions and systems described herein are also provided. |
申请人 |
INSMED INCORPORATED;LEIFER, FRANZISKA;OMIATEK, DONNA, M.;ONG, JANE;GUPTA, RENU;LI, ZHILLI;PERKINS, WALTER;MALININ, VLADIMIR |
发明人 |
LEIFER, FRANZISKA;OMIATEK, DONNA, M.;ONG, JANE;GUPTA, RENU;LI, ZHILLI;PERKINS, WALTER;MALININ, VLADIMIR |