| 发明名称 |
USE OF RHO GTPASE ACTIVATING TOXINS FOR THE TREATMENT AND/OR PREVENTION OF SYMPTOMATOLOGY ASSOCIATED WITH RETT SYNDROME |
| 摘要 |
<p>The invention concerns the use of a toxin selected from the group consisting of: type 1 (CNF1 ), type 2 (CNF2) or type 3 (CNF3) Cytotoxic Necrotizing Factor from Escherichia coli or CNFY from Yersinia spp. or DNT from Bordetella spp, active fragments or mixtures thereof for the preparation of a medicament for the treatment and/or prevention of symptomatology associated with Rett syndrome (RTT).</p> |
| 申请公布号 |
EP2536424(B1) |
申请公布日期 |
2014.06.04 |
| 申请号 |
EP20110713878 |
申请日期 |
2011.02.15 |
| 申请人 |
ISTITUTO SUPERIORE DI SANITÀ |
发明人 |
FIORENTINI, CARLA;LAVIOLA, GIOVANNI;RICCERI, LAURA;DE FILIPPIS, BIANCA;FABBRI, ALESSIA |
| 分类号 |
A61K38/16;A61P25/00 |
主分类号 |
A61K38/16 |
| 代理机构 |
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