| 摘要 |
A method of mass spectrometry is disclosed comprising mass analysing ions and obtaining mass spectral data and determining parent or precursor ions of interest. The method further comprises determining adduct or chemical artefact ions which have mass to charge ratios having a substantially linear relationship with the mass to charge ratio of the parent or precursor ions of interest, and removing or attenuating the first adduct or chemical artefact ions from the mass spectral data. The adduct or chemical artefact ions may comprise single or multiply charge ions, or ions that have lost or gained a neutral species or molecule. The invention recognises that noise lines exist in a MS-MS/MS heat map relating to a sample being analysed (see Fig. 1A), i.e. that significant sources of chemical noise may not be randomly distributed but can be intrinsically related to the parent ions of interest in a sample. |
