发明名称 PREPARATION WITH ELEVATED CONTENT
摘要 A composition for oral use, which contains a drug compound (in particular, a hardly water soluble or water-insoluble drug compound) in an elevated amount and is excellent in the absorbability of the drug compound via the digestive tract, is produced by dispersing the drug compound in an oily base and a surfactant in an amount exceeding the solubility thereof in the mixture of the oily base with the surfactant under heating, adding a polar solvent which serves as a poor solvent for the drug compound to the thus obtained dispersion, and heating the mixture to give a transparent liquid composition. Further, the obtained composition is encapsulated to give a capsule preparation.
申请公布号 EP1728505(B1) 申请公布日期 2014.06.04
申请号 EP20050727185 申请日期 2005.03.23
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 YOSHINARI, TOMOHIRO
分类号 A61K9/10;A61K9/107;A61K9/48;A61K31/4178;A61K47/02;A61K47/08;A61K47/10;A61K47/14;A61K47/34;A61K47/44;A61P31/18;C07D403/12 主分类号 A61K9/10
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