D-serine transporter inhibitors as pharmaceutical compositions for the treatment of central nervous system disorders

摘要

The present invention relates to pharmaceutical compositions comprising D-serine transporter inhibitors and therapeutic methods using such pharmaceutical compositions in methods for the treatment of central nervous system disorders.

主权项

1. A method for the alleviation of a central nervous system disorder which is schizophrenia caused by a deficit in N-methyl-D-aspartate receptor function, the method comprising administering to a subject in need thereof an acceptable pharmaceutical composition containing a therapeutically effective amount of at least one ASCT1 inhibitor compound, which is L-4-fluoro phenylglycine and at least one ASCT2 inhibitor compound, which is L-4-fluoro phenylglycine.