发明名称 |
Inhibitors of flaviviridae viruses |
摘要 |
Provided are compounds of Formula I:;
and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections (e.g. hepatitis C infections), particularly drug resistant Flaviviridae virus infections. |
申请公布号 |
US8741946(B2) |
申请公布日期 |
2014.06.03 |
申请号 |
US201213549130 |
申请日期 |
2012.07.13 |
申请人 |
Gilead Sciences, Inc. |
发明人 |
Watkins William J.;Canales Eda;Clarke Michael O'Neil Hanrahan;Doerffler Edward;Lazerwith Scott E. |
分类号 |
A61K31/381;C07D333/10 |
主分类号 |
A61K31/381 |
代理机构 |
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代理人 |
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主权项 |
1. A compound of Formula I:or a pharmaceutically acceptable salt or ester thereof, wherein:
R1 is H or methyl; and R2 is (C1-C6)alkyl; wherein each alkyl represents a straight or branched chain.
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地址 |
Foster City CA US |