Agent and methods for reducing inflammatory markers

摘要

A method for treating an autism spectrum condition includes administering an effective dose of a TNF-α inhibiting agent to a person having an autism spectrum condition or pervasive development disorder and at least one of elevated TNF-α in the cerebrospinal fluid or elevated TNF-α in the serum, as compared to normal conditions; and lowering at least one of the elevated TNF-α in the cerebrospinal fluid or elevated TNF-α in the serum. A TNF-α inhibiting agent includes at least one of Lenalinomide; Thalidomide; L-Carnosine; Infliximab; Etanercept; a stem cell preparation; derivatives thereof, isomers thereof, or pharmaceutically acceptable salts thereof.

主权项

1. A method for treating an autism spectrum disorder or pervasive development disorder, comprising:
administering an effective dose of a TNF-α inhibiting agent to a person having an autism spectrum disorder or pervasive development disorder and an elevated ratio of TNF-α in the cerebrospinal fluid to TNF-α in serum; and lowering the elevated ratio of TNF-α in the cerebrospinal fluid to TNF-α in the serum, wherein the TNF-α inhibiting agent is selected from the group consisting of lenalinomide; thalidomide; I-carnosine; infliximab; etanercept; and derivatives, isomers, or pharmaceutically acceptable salts of the TNF-α inhibiting agent.