发明名称 Polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methyl-benzoate hydrochloride, methods for preparing the same and use of the same
摘要 The present disclosure relates to polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the same.
申请公布号 US8741952(B2) 申请公布日期 2014.06.03
申请号 US201313846773 申请日期 2013.03.18
申请人 Shangong Luye Pharmaceutical Co., Ltd. 发明人 Li Youxin;Liu Wanhui;Lv Yang;Du Guanhua;Meng Qingguo;Yang Mina;Zhou Fengmei;Li Ju;Zhang Xuemei
分类号 A01N37/12;A01N37/44;A61K31/24;C07C229/00 主分类号 A01N37/12
代理机构 代理人
主权项 1. A crystal form I of [4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride], wherein the crystal form I exhibits a powder X-ray diffraction pattern obtained using CuKα radiation and having characteristic peaks expressed in degrees 2θ (±0.2° 2θ) at 10.690, 14.290, 16.030, 17.931, 19.009, 21.009 and 22.350.
地址 Yantai, Shandong CN