发明名称 |
COMPOSITIONS AND THEIR USES FOR ALLEVIATING PAIN |
摘要 |
The present invention provides a method for the long-term relief of chronic pain in a subject by activating in the subject an analgesic .alpha.-adrenergic receptor in the absence of .alpha.-2A receptor activation over a period of at least three days, such that relief of chronic pain is maintained in the absence of continued activation of said receptor. The analgesic .alpha.-adrenergic receptor can be, for example, the .alpha.-2B receptor. |
申请公布号 |
CA2486716(C) |
申请公布日期 |
2014.06.03 |
申请号 |
CA20032486716 |
申请日期 |
2003.04.23 |
申请人 |
ALLERGAN, INC. |
发明人 |
GIL, DANIEL W.;DONELLO, JOHN E. |
分类号 |
A61K31/538;G01N33/50;A61K31/137;A61K31/17;A61K31/4164;A61K31/4166;A61K31/4168;A61K31/4174;A61K31/4178;A61K31/421;A61K31/426;A61K31/433;A61K31/498;A61K45/06;A61P1/04;A61P3/10;A61P19/02;A61P25/02;A61P25/04;A61P25/06;A61P29/00;A61P29/02;A61P35/00;G01N33/15 |
主分类号 |
A61K31/538 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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