Disposable cartridge for fluid analysis

摘要

A disposable blood analysis cartridge for analyzing a blood sample including an optical absorbance measurement channel is described. The optical absorbance measurement channel includes a plasma separation region and at least one sub channel including a cuvette that is in fluid communication with the plasma separation region and configured to receive a plasma portion of a blood sample that has been passed through the plasma separation region. A negative pressure may be applied to the cartridge to draw the sample through the plasma separation region and into the sub channel including the cuvette.

主权项

1. A disposable blood analysis cartridge for analyzing a blood sample, comprising:
a microfluidics circuit having an optical scattering fluid measurement channel and an optical absorbance measurement channel; the optical absorbance measurement channel including:
a sample introduction region;a plasma separation region in fluid communication with the sample introduction region;a sub channel in fluid communication with the plasma separation region, the sub channel configured to receive a plasma portion of a blood sample that is introduced into the sample introduction region, after the blood sample has passed through the plasma separation region;the sub channel having a cuvette, and a gas permeable membrane downstream of the cuvette;a vacuum port situated downstream of the gas permeable membrane; and wherein a negative pressure applied to the vacuum port may draw the plasma portion of the blood sample from the plasma separation region, into the sub channel and to the cuvette, so that an optical absorbance of the plasma portion of the blood sample can be measured at the cuvette.