| 摘要 |
PURPOSE: A composition containing NecroX for suppressing cancer metastasis is provided to suppress the activation of Cdc42 or Rac1 or to reduce intracellular calcium concentration, thereby being used as a pharmaceutical composition or a food composition for suppressing cancer metastasis. CONSTITUTION: A composition for suppressing cancer metastasis contains NecroX which is selected among NecroX-1, NecroX-2, NecroX-5, NecroX-7, and NecroX-18. NecroX suppresses cancer metastasis by reducing cancer infiltration into tissues. The cancer infiltration into tissues is reduced by suppressing the expression of Rac1 and Cdc42 or reducing intracellular calcium concentration. |
