发明名称 ALKYLATED PIPERAZINE COMPOUNDS AS INHIBITORS OF BTK ACTIVITY.
摘要 <p>Alkylated piperazine compounds of Formula I are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.</p>
申请公布号 MX2014005289(A) 申请公布日期 2014.05.30
申请号 MX20140005289 申请日期 2012.11.02
申请人 F. HOFFMANN-LA ROCHE AG 发明人 WENDY B. YOUNG;JAMES JOHN CRAWFORD
分类号 C07D471/04;A61K31/381;A61K31/4985;A61P35/00;A61P37/00;C07D495/04;C07D519/00 主分类号 C07D471/04
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