发明名称 CHANNEL PROTEIN ACTIVATABLE LIPOSOMES
摘要 <p>Disclosed is a liposome, comprising a lipid bilayer enclosing a cavity, wherein the bilayer comprises a channel protein releasably linked to an eight-membered non-aromatic cyclic alkenylene group, preferably a cyclooctene group, and more preferably a trans-cyclooctene group. The liposomes are used in a kit comprising the liposome, the liposomal membrane of which comprises a channel protein linked to a Trigger, and an Activator for the Trigger, wherein the Trigger comprises the eight- membered non-aromatic cyclic alkenylene group, and the Activator comprises a diene.</p>
申请公布号 WO2014081300(A1) 申请公布日期 2014.05.30
申请号 WO2013NL50847 申请日期 2013.11.22
申请人 TAGWORKS PHARMACEUTICALS B.V. 发明人 ROBILLARD, MARC STEFAN;TEN HOEVE, WOLTER
分类号 A61K47/48;A61P35/00 主分类号 A61K47/48
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