| 摘要 |
<p>The invention relates to the compounds of formula I and formula II or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I or formula II; and methods for treating or preventing cardiovascular diseases may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of coronary heart diseases, hypertension, heart failure, inflammatory bowel disease, Tachycardia, Flutter, atrial fibrillation, atrial flutter, arryhthimias, valvular heart disease, stroke, cerebrovascular disease, ventricular fibrillation, QT prolongation, peripheral arterial disease, kidney diseases, diabetes related renal complications, hypertension, albuminuria, ESRD, Kidney GFR complications, Vascular Disease and Ventricular Septal Defect.</p> |
