发明名称 |
Method for predicting a therapy response in subjects with multiple sclerosis |
摘要 |
A method is provided for determining the efficacy of interferon -beta (IFN-β) therapy in a subject with multiple sclerosis. One step of the method can include obtaining a biological sample from the subject. After obtaining the biological sample, the expression level of at least one interferon-regulated gene (IRG) and/or variant thereof can be determined. Increased or decreased expression of the at least one IRG and/or variant thereof as compared to a control may indicate that the subject will respond poorly to IFN-βtherapy. |
申请公布号 |
AU2011268223(B2) |
申请公布日期 |
2014.05.29 |
申请号 |
AU20110268223 |
申请日期 |
2011.06.17 |
申请人 |
THE CLEVELAND CLINIC FOUNDATION |
发明人 |
RUDICK, RICHARD A.;RANSOHOFF, RICHARD M. |
分类号 |
A61K38/21;A61K38/17;A61K48/00;A61P29/00 |
主分类号 |
A61K38/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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