发明名称 Method For Predicting Effectiveness Of Angiogenesis Inhibitor
摘要 The purpose of the present invention is to provide a method for predicting the effectiveness of an angiogenesis inhibitor in a subject suffering from a tumor. Provided is a method comprising a step of testing for the presence or absence of an a mutation or loss of expression of B-Raf and PTEN in a sample of tumor tissue from the subject. By using the presence or absence of or a mutation or loss of expression of B-Raf and PTEN as an indicator, this method enables the antitumor effectiveness of the angiogenesis inhibitor to be predicted without administering the angiogenesis inhibitor to the subject.
申请公布号 US2014148483(A1) 申请公布日期 2014.05.29
申请号 US201214117276 申请日期 2012.05.16
申请人 EISAI R&D MANAGEMENT CO., LTD. 发明人 SEMBA TARO;NARITA YUSUKE;MINOSHIMA YUKINORI;YAMAGUCHI ATSUMI;ADACHI YUSUKE;YAMADA KAZUHIKO;MATSUI JUNJI;KADOWAKI TADASHI;TAKAHASHI KENTARO;FUNAHASHI YASUHIRO
分类号 C12Q1/68;A61K31/47 主分类号 C12Q1/68
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