发明名称 |
Method For Predicting Effectiveness Of Angiogenesis Inhibitor |
摘要 |
The purpose of the present invention is to provide a method for predicting the effectiveness of an angiogenesis inhibitor in a subject suffering from a tumor. Provided is a method comprising a step of testing for the presence or absence of an a mutation or loss of expression of B-Raf and PTEN in a sample of tumor tissue from the subject. By using the presence or absence of or a mutation or loss of expression of B-Raf and PTEN as an indicator, this method enables the antitumor effectiveness of the angiogenesis inhibitor to be predicted without administering the angiogenesis inhibitor to the subject. |
申请公布号 |
US2014148483(A1) |
申请公布日期 |
2014.05.29 |
申请号 |
US201214117276 |
申请日期 |
2012.05.16 |
申请人 |
EISAI R&D MANAGEMENT CO., LTD. |
发明人 |
SEMBA TARO;NARITA YUSUKE;MINOSHIMA YUKINORI;YAMAGUCHI ATSUMI;ADACHI YUSUKE;YAMADA KAZUHIKO;MATSUI JUNJI;KADOWAKI TADASHI;TAKAHASHI KENTARO;FUNAHASHI YASUHIRO |
分类号 |
C12Q1/68;A61K31/47 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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