发明名称 |
GPR17-MODULATING COMPOUNDS, DIAGNOSTIC AND THERAPEUTIC USES THEREOF |
摘要 |
Disclosed are compounds able to modulate the activity of the GPR17 receptor in a highly specific way, which are useful in the treatment and diagnosis of diseases or dysfunctions involving the activation of said receptor. In particular, the compounds according to the invention can be used for neuroprotective and/or reparatory purposes, in cerebral, cardiac and renal ischaemia, in cerebral trauma, in chronic neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), and in demyelinating diseases such as multiple sclerosis. |
申请公布号 |
US2014148472(A1) |
申请公布日期 |
2014.05.29 |
申请号 |
US201113883097 |
申请日期 |
2011.11.02 |
申请人 |
ABBRACCHIO MARIAPIA;EBERINI IVANO;PARRAVICINI CHIARA;MARTINI CLAUDIA;TRINCAVELLI MARIA LETIZIA;DANIELE SIMONA;CENTRO CARDIOLOGICO MONZINO SPA |
发明人 |
ABBRACCHIO MARIAPIA;EBERINI IVANO;PARRAVICINI CHIARA;MARTINI CLAUDIA;TRINCAVELLI MARIA LETIZIA;DANIELE SIMONA |
分类号 |
A61K31/519;A61K31/4192;A61K31/4196;A61K31/427;A61K31/4709 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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