| 发明名称 |
ANTI-CDH3 ANTIBODY HAVING HIGH INTERNALIZATION CAPACITY |
| 摘要 |
It is an object of the present invention to provide an anti-cadherin antibody having a high internalization capacity and provide an anti-cadherin antibody-drug conjugate that effectively kills cadherin-expressing cancer cells with the use of such antibody. The present invention provides an anti-cadherin antibody which recognizes a cadherin domain 1 (EC1) of cadherin and exhibits a high internalization capacity. |
| 申请公布号 |
EP2634194(A4) |
申请公布日期 |
2014.05.28 |
| 申请号 |
EP20110836461 |
申请日期 |
2011.10.28 |
| 申请人 |
PERSEUS PROTEOMICS INC. |
发明人 |
ISHII, KEISUKE;KATSUMI, KEIKO;MATSUURA, TADASHI;SUDO, YUKIO;MITOMO, KATSUYUKI;KOUDA, KATSUSHI |
| 分类号 |
C07K16/28;A61K39/395;A61K47/48;A61P35/00;C07K16/46;C12N5/10;C12N15/02;C12P21/08 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
