发明名称 Meldrum's acid, barbituric acid and pyrazolone derivatives substituted with hydroxylamine as hno donors
摘要 <p>The disclosed subject matter provides certain N-substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating, preventing, or delaying the onset and/or development of a disease or condition. In some embodiments, the disease or condition is selected from cardiovascular diseases, ischemia, reperfusion injury, cancerous disease, pulmonary hypertension and conditions responsive to nitroxyl therapy.</p>
申请公布号 IL232101(D0) 申请公布日期 2014.05.28
申请号 IL20140232101 申请日期 2014.04.13
申请人 THE JOHNS HOPKINS UNIVERSITY 发明人
分类号 C07D 主分类号 C07D
代理机构 代理人
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