METHODS OF PREDICTING HOST RESPONSIVENESS TO CANCER IMMUNOTHERAPIES BY EX VIVO INDUCTION OF LEUKOCYTE-FUNCTION-ASSOCIATED MRNAS

摘要

Embodiments of the invention relate generally to ex vivo methods of quantifying expression of leukocyte-function associated mRNAs and using the quantification to characterize an individual's potential responsiveness to cancer immunotherapy. Certain embodiments relate to methods to monitor the efficacy of ongoing cancer immunotherapy by evaluating expression of leukocyte-function associated mRNAs genes before and administration of an anti-cancer immunotherapy regimen.