发明名称 |
FORMULATIONS OF NANO-CARRIERS AND METHODS OF PREPARING THE SAME |
摘要 |
A method of preparing nano-carriers is disclosed. The method includes mixing an organic solution of a drug and an organic solution of a biological agent separately with a predetermined amount of water having one or more dissolved surfactants to obtain a first mixture and a second mixture respectively. Subsequently, the first mixture and the second mixture are homogenized separately to obtain a solution of nano-crystals of the drug and a solution of nano-particles of the biological agent respectively. Thereafter, the solution of nano-crystals of the drug and the solution of nano-particles of the biological agent are together subjected to an ultra-sound homogenization to obtain a solution of nano-carriers. An interfacial extraction and/or a dialysis are then performed on the solution of nano-carriers to obtain the nano-carriers. Formulations of the nano-carriers are also disclosed. |
申请公布号 |
EP2525782(A4) |
申请公布日期 |
2014.05.28 |
申请号 |
EP20110732743 |
申请日期 |
2011.01.06 |
申请人 |
CONCEPT MEDICAL RESEARCH PRIVATE LIMITED;ENVISION SCIENTIFIC PRIVATE LIMITED |
发明人 |
DOSHI, MANISH;SHERDIWALA, DIVYESH;SOJITRA, PRAKASH |
分类号 |
A61K9/14;A61K9/51;A61K31/436;A61K47/06;A61K47/14 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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