发明名称 |
Targeting PAX2 for the induction of DEFB1-mediated tumor immunity and cancer therapy |
摘要 |
Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. |
申请公布号 |
US8735365(B2) |
申请公布日期 |
2014.05.27 |
申请号 |
US201113005579 |
申请日期 |
2011.01.13 |
申请人 |
DONALD CARLTON D.;PHIGENIX, INC. |
发明人 |
DONALD CARLTON D. |
分类号 |
A01N43/04;C07H21/04;C12N15/00;C12N15/63;C12N15/86 |
主分类号 |
A01N43/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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