发明名称 |
Isolated fungal promoters and gene transcription terminators and methods of protein and chemical production in a fungus |
摘要 |
The present invention encompasses isolated gene regulatory elements and gene transcription terminators that are differentially expressed in a native fungus exhibiting a first morphology relative to the native fungus exhibiting a second morphology. The invention also encompasses a method of utilizing a fungus for protein or chemical production. A transformed fungus is produced by transforming a fungus with a recombinant polynucleotide molecule. The recombinant polynucleotide molecule contains an isolated polynucleotide sequence linked operably to another molecule comprising a coding region of a gene of interest. The gene regulatory element and gene transcription terminator may temporally and spatially regulate expression of particular genes for optimum production of compounds of interest in a transgenic fungus. |
申请公布号 |
US8735562(B2) |
申请公布日期 |
2014.05.27 |
申请号 |
US20080257261 |
申请日期 |
2008.10.23 |
申请人 |
DAI ZIYU;LASURE LINDA L.;MAGNUSON JON K.;BATTELLE MEMORIAL INSTITUTE |
发明人 |
DAI ZIYU;LASURE LINDA L.;MAGNUSON JON K. |
分类号 |
C07H21/04;C12N15/63 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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