Gene finding using ordered sets of distinct marker strings

摘要

A method and system for finding in a DNA sequence, a gene represented by an ordered set of marker strings is disclosed. Sub-strings in the DNA sequence matching each marker string are identified. In a set ordered via occurrence of the marker strings in the ordered set of marker strings, the score and position of each sub-string whose score satisfies a matching constraint is recorded. For each except the last marker string, directed links are created between each identified sub-string that matches the marker string and any identified sub-strings that match the subsequent marker string, subject to the directed links satisfying an inter-marker length constraint. Traced are all paths that connect each identified sub-string that matches the first marker string to an identified sub-string that matches the last marker string using the directed links. The paths satisfy a sequence length constraint and are stored in memory of a computer system.