发明名称 Quinazoline derivatives as tyrosine kinase inhibitors
摘要 The invention concerns quinazoline derivatives of the Formula I, or pharmaceutically acceptable salts thereof: wherein each of R1, R2, R3, R4 and m are as defined in the description; processes for their preparation; pharmaceutical compositions containing them and their use in the manufacture of a medicament for providing an anti-proliferative effect. The quinazoline derivatives of Formula I are expected to be useful in the treatment of diseases such as certain cancers mediated by erbB receptor tyrosine kinases, and, for example, EGFR tyrosine kinase.
申请公布号 US8735410(B2) 申请公布日期 2014.05.27
申请号 US20060884923 申请日期 2006.02.24
申请人 HALSALL CHRISTOPHER THOMAS;HENNEQUIN LAURENT FRANCOIS ANDRE;PLOWRIGHT ALLEYN THOMAS;STOREY RICHARD;LENNON KIERAN;ASTRAZENECA AB 发明人 HALSALL CHRISTOPHER THOMAS;HENNEQUIN LAURENT FRANCOIS ANDRE;PLOWRIGHT ALLEYN THOMAS;STOREY RICHARD;LENNON KIERAN
分类号 A01N43/54;A61K31/517 主分类号 A01N43/54
代理机构 代理人
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