| 摘要 |
It is intended to provide a method capable of producing a desired fast disintegrating tablet with good compression efficiency regardless of the kind of an active ingredient to be contained or the kind of other ingredient to be added and a fast disintegrating tablet obtained by the production method, which is a dry direct compression fast disintegrating tablet obtained by the direct compression of a mixture obtained by mixing a granulated matter obtained by mixing one or more corrigents selected from the group consisting of erythritol, xylitol, mannitol, lactose and sucrose and one or more binder powders selected from the group consisting of crystalline cellulose, crystalline cellulose carmellose sodium and carmellose potassium followed by granulating the mixture using a fluidized bed granulator while spraying an aqueous solution of reduced maltose syrup, an active ingredient, an excipient, a disintegrant, a fluidizer and a lubricant, and particularly, a dry direct compression fast disintegrating tablet containing zolpidem tartrate or meloxicam. |
