Functionalized Magnetic Nanoparticles and Use in Imaging Amyloid Deposits and Neurofibrillary Tangles

摘要

The present disclosure provides functionalized magnetic nanoparticles (MNPs) comprising a functional group that binds toβ-amyloid deposits and/or neurofibrillary tangles. The present disclosure provides compositions comprising the functionalized MNPs, and methods of using the functionalized MNPs in imagingβ-amyloid deposits and neurofibrillary tangles.