发明名称 CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT
摘要 Novel cromolyn analogs useful as imaging agents for detecting atherosclerotic plaques and for treating atherosclerosis and Alzheimer's Disease, and methods of making the cromolyn analogs, are disclosed. The cromolyn analogs have the general formula: wherein X is OH, C1-C6 alkoxyl; Y and Z are independently selected from a C1-C6 alkyl, C1-C6 alkoxyl, halogen, un-substituted or C1-C6 substituted amine, 18F, 19F, or H; and n is 1, 2, or 3; and wherein for structure (I), if n are both 1 and Y and Z are both H and X is OH.
申请公布号 US2014140927(A1) 申请公布日期 2014.05.22
申请号 US201314059924 申请日期 2013.10.22
申请人 ELMALEH DAVID R.;SHOUP TIMOTHY;THE GENERAL HOSPITAL CORPORATION 发明人 ELMALEH DAVID R.;SHOUP TIMOTHY
分类号 A61K51/04;C07D311/24 主分类号 A61K51/04
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