摘要 |
Compounds of Formula I: or stereoisomers, tautomers, or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Ring A, Ring C and X are as defined herein, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome. |
申请人 |
ARRAY BIOPHARMA INC.;ALLEN, SHELLEY;ANDREWS, STEVEN, WADE;BLAKE, JAMES, F.;BRANDHUBER, BARBARA, J.;HAAS, JULIA;JIANG, YUTONG;KERCHER, TIMOTHY;KOLAKOWSKI, GABRIELLE, R.;THOMAS, ALLEN, A.;WINSKI, SHANNON, L. |
发明人 |
ALLEN, SHELLEY;ANDREWS, STEVEN, WADE;BLAKE, JAMES, F.;BRANDHUBER, BARBARA, J.;HAAS, JULIA;JIANG, YUTONG;KERCHER, TIMOTHY;KOLAKOWSKI, GABRIELLE, R.;THOMAS, ALLEN, A.;WINSKI, SHANNON, L. |