发明名称 |
A chemo-enzymatic approach to the synthesis of pimecrolimus |
摘要 |
Processes for preparing pimecrolimus starting from ascomycin, exploiting the selectivity characteristics of the purified enzymatic systems particularly regarding the selective functionalization of the hydroxyl groups present in position 24 and 33 of ascomycin. Such method represents the first example of chemoenzymatic synthesis for preparing pimecrolimus. |
申请公布号 |
AU2010250802(B2) |
申请公布日期 |
2014.05.22 |
申请号 |
AU20100250802 |
申请日期 |
2010.05.19 |
申请人 |
EUTICALS SPA |
发明人 |
GRISENTI, PARIDE;REZA ELAHI, SHAHRZAD;VERZA, ELISA |
分类号 |
C07H19/01 |
主分类号 |
C07H19/01 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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