| 发明名称 |
2 -ALKYNYL SUBSTITUTED NUCLEOSIDE DERIVATIVES FOR TREATING VIRAL DISEASES |
| 摘要 |
The present invention relates to 2'-Alkynyl Substituted Nucleoside Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein B, X, R1, R2, R3 and R4 are as defined herein. The present invention also relates to compositions comprising at least one 2'-Alkynyl Substituted Nucleoside Derivative, and methods of using the 2'-Alkynyl Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient. |
| 申请公布号 |
CA2891125(A1) |
申请公布日期 |
2014.05.22 |
| 申请号 |
CA20132891125 |
申请日期 |
2013.11.14 |
| 申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
BENNETT, FRANK;HUANG, YUHUA;WANG, LINGYAN;BOGEN, STEPHANE L.;KEREKES, ANGELA D.;GIRIJAVALLABHAN, VINAY M.;BUTORA, GABOR;TRUONG, QUANG;DAVIES, IAN;WEBER, ANNE E. |
| 分类号 |
A61K31/7068;C07H19/02;C07H19/10 |
主分类号 |
A61K31/7068 |
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