The present invention relates to recombinant adenoviruses and vectors thereof. In particular, the adenoviruses are novel simian adenoviruses having a low seroprevalence and high immunogenicity relative to other adenoviruses and vectors thereof. The invention also provides methods for production of the adenoviruses and for the treatment of diseases by administering the adenoviral vector(s) to a subject (e.g., a human).
申请公布号
WO2014078688(A2)
申请公布日期
2014.05.22
申请号
WO2013US70353
申请日期
2013.11.15
申请人
BETH ISRAEL DEACONESS MEDICAL CENTER, INC.;WASHINGTON UNIVERSITY