Energy Absorbing-Based Diagnostic and Therapeutic Methods Employing Nucleic Acid Molecules Encoding Chromophore-Producing Enzymes

摘要

Provided are diagnostic and therapeutic methods using a composition containing a nucleic acid encoding a chromophore-producing enzyme(s), such as a melanin-producing enzyme or enzymes. The nucleic acid molecules can be used for directed or localized delivery to tumors or other cells associated with disease resulting in production of a chromophore product that can be used for diagnosis and therapy, including of tumors and metastases.