AGENTS FOR TREATMENT OF CLAUDIN EXPRESSING CANCER DISEASES
摘要
The present invention provides binding agents that contain a binding domain that is specific for CD3 allowing binding to T cells and a binding domain that is specific for a tumor-associated claudin molecule and methods of using these binding agents or nucleic acids encoding therefor for treating cancer.
申请公布号
WO2014075697(A1)
申请公布日期
2014.05.22
申请号
WO2012EP04712
申请日期
2012.11.13
申请人
BIONTECH AG;GANYMED PHARMACEUTICALS AG;TRON - TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITÄTSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITÄT MAINZGEMEINNÜTZIGE GMBH
发明人
SAHIN, UGUR;TÜRECI, ÖZLEM;STADLER, CHRISTIANE;HOLLAND, JULIA;BÄHR-MAHMUD, HAYAT