Process for the Preparation of Compositions for Modulating a Kinase Cascade and Methods of Use Thereof
摘要
The invention relates to compositions comprising 2-(5-(4-(2- morpholinoethoxy)phenyl)pyridin 2-yl)-N-benzylacetamide and its mesylate and dihydrochloride salts. More specifically, the invention provides an efficient process for the synthesis of 2-)5-<4-)2 morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide and its mesylate and dihydrochloride salts and methods for modulating one or more components of a kinase cascade using the compositions of the invention.
申请公布号
AU2014202221(A1)
申请公布日期
2014.05.22
申请号
AU20140202221
申请日期
2014.04.23
申请人
KINEX PHARMACEUTICALS, LLC
发明人
HANGAUER JR., DAVID G.;COUGHLIN, DANIEL;CODY, JEREMY A.;GALE, JONATHAN;PATRA, DEBASIS;PALMER, GRANT J.;ISBESTER, PAUL K.;SALSBURY, JONATHON