发明名称 |
QUINOLINES AND AZA-QUINOLINES AS CRTH2 RECEPTOR MODULATORS |
摘要 |
The invention provides certain quinolines and aza-quinolines of the Formula (I), and their pharmaceutically acceptable salts, wherein E, J1, Ja, Jb, R2, R3, R22, Ra, Rb, Rc, Rd, X, Y, b, n, and q are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTH2 function. |
申请公布号 |
EP2661265(A4) |
申请公布日期 |
2014.05.21 |
申请号 |
EP20110850226 |
申请日期 |
2011.12.19 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
BOYCE, CHRISTOPHER, W.;FEVRIER, SALEM;MCCORMICK, KEVIN, D.;PALANI, ANANDAN;ASLANIAN, ROBERT, G.;SILIPHAIVANH, PHIENG;METHOT, JOEY, L.;BROWN, WILLIAM COLBY;VACCARO, HENRY |
分类号 |
C07D215/48;A61K31/47;A61P11/00;C07D401/06;C07D401/12;C07D405/12;C07D471/04;C07D491/107 |
主分类号 |
C07D215/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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