发明名称 NOVEL ANTIFUNGAL 5,6-DIHYDRO-4-[(DIFLUORETHYL)PHENYL]-4H-PYRROLO[1,2-A][1,4]BENZODIAZEPAN AND 4-(DIFLUORETHYL)PHENYL-6H-PYRROLO[1,2-A][1,4]BENZODIAZEPIN DERIVATIVES.
摘要 The present invention concerns novel compounds of Formula (I): wherein R1, R2, R3, R4, R5 and R6 have the meaning defined in the claims. The compounds according to the present invention are active mainly against dermatophytes and systemic fungal infections. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
申请公布号 EP2576557(B1) 申请公布日期 2014.05.21
申请号 EP20110723445 申请日期 2011.06.01
申请人 JANSSEN PHARMACEUTICA, N.V. 发明人 MEERPOEL, LIEVEN;MAES, LOUIS, JULES,ROGER, MARIE;DE WIT, KELLY
分类号 C07D487/04;A61K31/5517;A61P31/10 主分类号 C07D487/04
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