发明名称 |
SUBSTITUTED ANDROST-4-ENE DIONES |
摘要 |
The disclosure relates to novel C4 and C6 substituted androst-4-ene diones as well as andros-1,4-diene diones and derivatives thereof, their process of preparation, pharmaceutical compounds containing them, and the use of said compounds for the treatment of hormone-related disorders in mammals. This includes hormone-dependent cancers, particularly those caused by elevated levels of estrogen and its intermediates. These compounds can also be used in the treatment of other hormone-related disorders, including benign prostatic hyperplasia, cardiovascular disease, and neurodegenerative disorders. |
申请公布号 |
EP2556082(A4) |
申请公布日期 |
2014.05.21 |
申请号 |
EP20110766695 |
申请日期 |
2011.04.07 |
申请人 |
EMORY UNIVERSITY;HAUPTMAN-WOODWARD MEDICAL RESEARCH INSTITUTE, INC.;THE RESEARCH FOUNDATION OF STATE OF NEW YORK |
发明人 |
DAVIES, HUW;GHOSH, DEBASHIS;MORTON, DANIEL |
分类号 |
C07J1/00;A61K31/566;A61P5/00;A61P35/00 |
主分类号 |
C07J1/00 |
代理机构 |
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代理人 |
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