发明名称 |
Fluorescent imaging agents |
摘要 |
Provided is a family of intramolecularly quenched imaging agents for use in both in vivo and in vitro imaging that contain at least one enzymatically cleavable oligopeptide and two fluorophores or a fluorophore and a quencher. When subjected to proteolytic cleavage, at least one fluorophore is unquenched and becomes capable of producing a fluorescent signal upon excitation with light of an appropriate wavelength. Also provided are in vivo and in vitro imaging methods using such imaging agents. |
申请公布号 |
EP2732826(A1) |
申请公布日期 |
2014.05.21 |
申请号 |
EP20130185417 |
申请日期 |
2009.01.17 |
申请人 |
VISEN MEDICAL, INC. |
发明人 |
RAJOPADHYE, MILIND;GROVES, KEVIN;PREDA, DORIN V |
分类号 |
A61K49/00;A61K49/04 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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