发明名称 |
METHOD FOR PREPARING A POLYVALENT-IMMUNOGLOBULIN CONCENTRATE |
摘要 |
The present invention relates to a method for preparing a concentrate of polyvalent immunoglobulins with view to therapeutic use, from an initial solution of blood plasma or a plasma fraction enriched with immunoglobulins, comprising the steps for removing the protein contaminants by precipitation with caprylic acid in order to obtain a solution free of proteases, and for separating by chromatography on a fluidized bed the solution free of proteases, said method allowing a concentrate of human polyvalent immunoglobulins with a yield of more than 4.5 g of immunoglobulins per liter of blood plasma applied to be obtained. |
申请公布号 |
EP2731966(A1) |
申请公布日期 |
2014.05.21 |
申请号 |
EP20120733726 |
申请日期 |
2012.07.11 |
申请人 |
LABORATOIRE FRANÇAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES |
发明人 |
CHTOUROU, ABDESSATAR;BATAILLE, DAMIEN;MICHAUX, GEORGES |
分类号 |
C07K16/06;C07K1/36 |
主分类号 |
C07K16/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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