发明名称 |
Method of producing proteins comprising unnatural amino acid |
摘要 |
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNAsynthetases, pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided. |
申请公布号 |
EP2392923(B1) |
申请公布日期 |
2014.05.21 |
申请号 |
EP20110165139 |
申请日期 |
2004.04.16 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
DEITERS, ALEXANDER;CROPP, ASHTON T.;CHIN, JASON W.;ANDERSON, CHRISTOPHER J.;SCHULTZ, PETER G. |
分类号 |
C07C269/06;C07C227/22;C07C229/36;C07C311/41;C07K1/107;C07K1/13;C07K14/00;C07K14/01;C07K16/18;C09B11/08;C09B57/00;C12N;C12N9/00;C12N9/16;C12N15/67;C12P17/04;C12P21/02;C12P21/06;G01N33/532 |
主分类号 |
C07C269/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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