| 发明名称 |
4 - PIPERIDINYL COMPOUNDS FOR USE AS TANKYRASE INHIBITORS |
| 摘要 |
<p>The present invention provides for compounds of formula (I): wherein R1-R4 and n are defined herein. The present invention also provides for pharmaceutical compositions and combinations comprising a compound of formula (I) as well as for the use of such compounds as tankyrase inhibitors and in the treatment of Wnt signaling and tankyrase 1 and 2 signaling related disorders which include, but are not limited to, cancer.</p> |
| 申请公布号 |
EP2731940(A1) |
申请公布日期 |
2014.05.21 |
| 申请号 |
EP20120742957 |
申请日期 |
2012.07.13 |
| 申请人 |
NOVARTIS AG |
发明人 |
CHEN, CHRISTINE HIU-TUNG;CHIN, NOEL CHIN;DIPIETRO, LUCIAN V.;FAN, JIANME;PALERMO, MARK G;SHULTZ, MICHAEL DAVID;TOURE, BAKARY-BARRY |
| 分类号 |
C07D401/04;A61K31/4523;A61K35/00;C07D401/14;C07D471/04;C07D487/04;C07D491/04;C07D495/04;C07D498/04;C07D513/04 |
主分类号 |
C07D401/04 |
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