| 发明名称 |
NEW THIO DERIVATIVES BEARING LACTAMS AS POTENT HDAC INHIBITORS AND THEIR USES AS MEDICAMENTS. |
| 摘要 |
<p>The present invention relates to novel amide compounds of Formula (I), and their use as anti-tumoral and pro-apoptotic agents. The invention includes the use of such compounds in medicine, in relation to cancer disease as well as other diseases where an inhibition of HDAC is responsive, and the pharmaceutical composition containing such compounds.</p> |
| 申请公布号 |
MX2014003334(A) |
申请公布日期 |
2014.05.21 |
| 申请号 |
MX20140003334 |
申请日期 |
2012.09.17 |
| 申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. |
发明人 |
GIUSEPPE GIANNINI;WALTER CABRI;GIANFRANCO BATTISTUZZI;DAVIDE VIGNOLA;NICOLA FANTO;CLAUDIO PISANO;LOREDANA VESCI |
| 分类号 |
C07D205/08;A61K31/397;A61K31/4015;A61K31/45;A61K31/4709;A61P25/00;A61P29/00;A61P33/00;A61P35/00;C07D207/277;C07D207/28;C07D211/78;C07D401/04 |
主分类号 |
C07D205/08 |
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