COMPOSITIONS COMPRISING AGENTS THAT INHIBIT NEUROPILIN AND TOLLOID LIKE 2

摘要

We disclose agents that inhibit the expression of NETO-2 which has elevated expression in cancer stem cells; the use of NETO- 2 as a diagnostic or prognostic marker of tumour initiation; the use NETO-2 polypeptides in the identification of agents that inhibit activity; and including antibodies that bind NETO-2 and vaccines comprising NETO-2 polypeptides.