发明名称 |
4-OXO-3,5,7,8-TETRAHYDRO-4H-PYRANO {4,3-D} PYRMINIDINYL COMPOUNDS FOR USE AS TANKYRASE INHIBITORS |
摘要 |
<p>The present invention provides for compounds of formula (I) wherein R1 and R2 are defined herein. The present invention also provides for pharmaceutical compositions and combinations comprising a compound of formula (I) as well as for the use of such compounds as tankyrase inhibitors and in the treatment of Wnt signaling and tankyrase 1 and 2 signaling related disorders which include, but are not limited to, cancer.</p> |
申请公布号 |
EP2731951(A1) |
申请公布日期 |
2014.05.21 |
申请号 |
EP20120742995 |
申请日期 |
2012.07.13 |
申请人 |
NOVARTIS AG |
发明人 |
CHEUNG, ATWOOD, KIM;CHIN, DONOVAL, NOEL;FAN, JIANMEI;SHULTZ, MICHAEL, DAVID;TOMLINSON, RONALD, CHARLES |
分类号 |
C07D491/052;A61K31/519;A61P35/00 |
主分类号 |
C07D491/052 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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