| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to compounds of formula(I), wherein Rrepresents an alkoxy group or halogen; each U and V independently represents CH or N; "----" means a bond or is absent; W represents CH or N, or if "----" is absent, then W represents CHor NH, provided not all U, V and W represent N; A represents a bond or CH; Rrepresents H, or provided A means CH, then it also can represent OH; each m and n are independently equal to 0 or 1; D represents CHor a bond; G represents a phenyl group that is single or double substituted in meta- and/or para-position(s) by substitutes specified in alkyl, Calkoxy group and halogen, or G represents one of the groupsGandG: wherein each Z, Zand Zrepresents CH; and X represents N or CH and Q represents O or S; it should be noted that provided each m and n are equal to 0, then A represents CH; or a pharmaceutically acceptable salt of such compound. Besides, the invention refers to a pharmaceutical composition for treating a bacterial infection containing an active ingredient presented by a compound of formula (I) or a pharmaceutically acceptable salt thereof, and at least one therapeutically inert additive.EFFECT: preparing the oxazolidine compounds applicable for preparing a drug for treating and preventing the bacterial infections.14 cl, 8 dwg, 2 tbl, 33 ex |
