发明名称 |
Method for the production of 2-hydroxy-4-(methylthio)butyronitrile from 3-(methylthio)propanal and hydrogen cyanide |
摘要 |
A method for the production of 2-hydroxy-4-(methylthio)butyronitrile having good storage stability in a multi-zone reactor, is provided. 3-methylmercaptopropionaldehyde is reacted with hydrogen cyanide in the presence of a base as catalyst in a main reaction zone of the multizone reactor to form a reaction mixture comprising the 2-hydroxy-4-(methylthio)butyronitrile, unreacted 3-methylmercaptopropionaldehyde, the catalyst and residual amounts of gaseous hydrogen cyanide. The residual gaseous hydrogen cyanide is removed from the main reaction zone to an absorption and post-reaction zone of the reactor which comprises a mixture of 3-methylmercaptopropionaldehyde and the catalyst; and the gaseous hydrogen cyanide is further reacted with the 3-methylmercaptopropionaldehyde in the absorption and post reaction zone. A molar ratio of hydrogen cyanide to 3-(methylthio)propanal in the main reaction zone is from 0.98 to 1.03. |
申请公布号 |
US8729288(B2) |
申请公布日期 |
2014.05.20 |
申请号 |
US201213402041 |
申请日期 |
2012.02.22 |
申请人 |
BUSS DIETER;STEURENTHALER MARTIN;RINNER MICHAEL R.;KRETZ STEPHAN;HASSELBACH HANS JOACHIM;FINKELDEI CASPAR-HEINRICH;KOERFER MARTIN;ZACCHI PABLO;EVONIK DEGUSSA GMBH |
发明人 |
BUSS DIETER;STEURENTHALER MARTIN;RINNER MICHAEL R.;KRETZ STEPHAN;HASSELBACH HANS JOACHIM;FINKELDEI CASPAR-HEINRICH;KOERFER MARTIN;ZACCHI PABLO |
分类号 |
C07C253/00;C07C51/08 |
主分类号 |
C07C253/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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