发明名称 |
Monoclonal antibody and its use for the identification of the oncofetal isoform of fibronectin (B-FN) for diagnosis or therapy |
摘要 |
Epitopes localized on FNIII-8 repeat that are normally cryptic but are unmasked by insertion of FNIII-B into the FN molecule and are recognized by specific ligands are described; antibodies or their fragments able to identify the above said epitope are also described. |
申请公布号 |
US8728740(B2) |
申请公布日期 |
2014.05.20 |
申请号 |
US200913139112 |
申请日期 |
2009.12.11 |
申请人 |
CASTELLANI PATRIZIA;SASSI FRANCESCA;CARNEMOLLA M. BARBARA;BORSI LAURA;BALZA ENRICA;SIRIUS-BIOTECH S.R.L. |
发明人 |
CASTELLANI PATRIZIA;SASSI FRANCESCA;CARNEMOLLA M. BARBARA;BORSI LAURA;BALZA ENRICA |
分类号 |
G01N33/53 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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