| 摘要 |
FIELD: measurement equipment.SUBSTANCE: invention relates to measurement equipment, namely, to optical methods for registration of particle aggregation during performance of immunochemical reactions, for instance, using particles of micron size with reagents immobilised on them. During the reaction such particles are aggregated, formation of aggregates is recorded by turbidimetric or nephelometric method. Due to large size of initial particles their mutual approaching due to Brownian motion is slow, and formation of aggregates takes place in a non-uniform manner in the reaction volume, therefore to increase speed of aggregation and accuracy of its supervision the suspension of reagents must be mixed. Mixing is carried out by or at the expense of cyclic movement of magnetic particles placed into the mix, or the mix flow in the mode of flooded jet, or by means of reciprocal movement of the mix along the cuvette.EFFECT: method accelerates the reaction and increases accuracy of measured kinetics.5 cl, 6 dwg |
